529 results

Autoimmune uveitis: study of treatment therapies

Alessandra Gonçalves Commodaro, Luciana de Deus Vieira de Moraes, Denise Vilarinho Tambourgi, Rubens Belfort Jr., Osvaldo Augusto Sant’Anna, Luiz Vicente Rizzo

DOI: 10.1590/s1679-45082010rb1416

ABSTRACTExperimental autoimmune uveitis is an organ-specific T-cell mediated autoimmune disease characterized by inflammation and consequent destruction of the neural retina and adjacent tissues. Inflammation in experimental autoimmune uveitis may be induced in rodents by immunization with retinal antigens, such as interphotoreceptor retinoid-binding protein. We present a review of experimental studies that correlate primary immunobiological functions with this chronic disease and the possible use of molecules for the treatment of autoimmune uveitis.

Can the lymph node reactivity pattern in the pN0 neck analysis provide any additional prognostic information in patients with laryngeal squamous cell carcinoma?

Gabriel Manfro, Claudio Cernea, Paulo Antônio Silvestre de Faria, Fernando Vaz Agarez, Fernando Luiz Dias, Roberto Araújo Lima, [...]

DOI: 10.1590/s1679-45082010ao1429

ABSTRACTObjective:To evaluate the influence of lymph node reactivity on recurrence and survival rates in a population of pT3 or pT4 pN0 patients with laryngeal squamous cell carcinoma.Methods:Between 2002 and 2005, 105 patients with LSSC underwent total laryngectomy with bilateral selective neck dissection including levels II, III and IV. Most (69) received PO radiotherapy. All pathological specimens were either pT3 or pT4, and all necks were pN0. All lymph nodes were analyzed and their reactivity status were classified as the following […]

Relation between three-dimensional and two-dimensional echocardiography and biochemical analysis in patients with ST-segment elevation myocardial infarction percutaneously treated

Marcelo Luiz Campos Vieira, Wercules Antônio Oliveira, Alexandre Ferreira Cury, Adriana Cordovil, Ana Clara Tude Rodrigues, Gustavo Alberto Frazatto Naccarato, [...]

DOI: 10.1590/s1679-45082010ao1438

ABSTRACTObjective:The prognosis of patients with acute myocardial infarction depends on multiple features that can demonstrate myocardial injury degree (such as serum markers of cardiac necrosis), and also on adaptive mechanisms relative to the acute event. The aim of the study was to assess the relation between biochemical and echocardiographic findings from three-dimensional echocardiographic (3D Echo) analysis and echocardiographic two-dimensional (2D Echo) left ventricular ejection fraction in patients with ST-segment elevation acute myocardial infarction, submitted to primary percutaneous treatment.Methods:A prospective study […]

Integrative review: what is it? How to do it?

Marcela Tavares de Souza, Michelly Dias da Silva, Rachel de Carvalho

DOI: 10.1590/s1679-45082010rw1134

ABSTRACTIntroduction: The integrative review is the methodology that provides synthesis of knowledge and applicability of results of significant studies to practice.Objective:To present the phases of an integrative review and the relevant aspects to be taken into account when using this methodological resource.Methods:This study was based on bibliographic search and on the experience of the authors when performing an integrative review.Results:Presentation of the six stages of the integrative review process: preparing the guiding question, searching or sampling the literature, data collection, […]

Pilot study in neonates using low-level laser therapy in the immediate postoperative period of myelomeningocele

Nathali Cordeiro Pinto, Fernando Campos Gomes Pinto, Eduardo Joaquim Lopes Alho, Elisabeth Matheus Yoshimura, Vera Lucia Jornada Krebs, Manoel Jacobsen Teixeira, [...]

DOI: 10.1590/s1679-45082010ao1441

ABSTRACTObjective:To analyze the tissue repair behavior after corrective surgical incision in neonates submitted to low-level laser therapy, in an attempt to diminish the incidence of postoperative dehiscence following the surgery for myelomeningocele performed immediately after birth.Methods:It is a prospective pilot study with 13 myelomeningocele patients submitted to surgery at birth who received adjuvant treatment with low-level laser therapy (Group A). Diode laser C.W., λ = 685t nm, p = 21 mW, E = 0.19 J was punctually applied along the […]

Evaluation of the behavior of the preschool one just admitted in the unit of pediatrics and the use of the therapeutic toy

Mariana Coelho Campos, Karen Cristina S. Rodrigues, Marcia Carla Morete Pinto

DOI: 10.1590/s1679-45082010ao1462

ABSTRACTObjective:To evaluate the behavior of children before and after a therapeutic play session.Methods:A quantitative and descriptive study was carried out in a major hospital of the city of Santos, State of São Paulo, involving 30 preschool children recently admitted to a pediatric ward. A behavior scale was applied before and after a therapeutic play session. This scale comprises six categories: moving, gazing, expressing feelings, talking, playing, and not responding to stimuli or requests. Each category is scored from 1 to […]

The impact of motivational interventions for increasing physical activity

Aneci Sobral Rocha, Marcio Marega

DOI: 10.1590/s1679-45082010ao1442

ABSTRACTObjective:To assess whether incentives for practicing regular physical activities in fact help raising the frequency of exercising.Methods:Male and female subjects undergoing two to three assessments in the Check-Up Unit of Hospital Israelita Albert Einstein (HIAE) were evaluated by noting any increase in levels of physical activity, improvements in mean metabolic unit numbers, and the sensitization index. The International Physical Activity Questionnaire was applied to assess the sample.Results:There were 1,879 subjects − 1,559 (83%) males and 320 (17%) females – aged […]

Magnetic resonance imaging findings in adnexial torsion

Ronald Meira Castro Trindade, Ronaldo Hueb Baroni, Michelle Rosemberg, Marianne Siquara de Quadros, Marcelo de Castro Jorge Racy, Adriano Tachibana, [...]

DOI: 10.1590/s1679-45082010rc878

ABSTRACTAdnexial torsion is an unusual event, but a major cause of abdominal pain in women. It is often associated with ovarian tumor or cyst, but can occur in normal ovaries, especially in children. The twisting of adnexial structures may involve the ovary or tube, but frequently affects both. In most cases, it is unilateral, with slight predilection for the right side. In imaging findings, increased ovarian volume and adnexial masses are observed, with reduced or absent vascularization. In cases of […]

En bloc pancreaticoduodenectomy and right hemicolectomy to treat locally advanced right colon cancer: report of three cases

Sergio Renato Pais Costa, Sergio Henrique Couto Horta, Alexandre Cruz Henriques, Jaques Waisberg, Manlio Basílio Speranzini

DOI: 10.1590/s1679-45082010rc786

ABSTRACTAlthough colorectal tumors are fairly common surgical conditions, 5 to 12% of these tumors are locally advanced (T4 tumors) upon diagnosis. In this particular situation, the efficacy of en bloc multivisceral resection has been proven. When right-colon cancer invades the proximal duodenum or even the pancreatic head, a challenging dilemma arises due to complexity of the curative surgical procedure. Therefore, en bloc pancreaticoduodenectomy with right hemicolectomy should be performed to obtain free margins. The present study reports three cases of […]

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