550 results

Administration of BAY 41-2272 prevents bladder dysfunction in nitric-oxide deficient rats

Carlos Arturo Levi D'Ancona, Fabíola Zakia Taufic Mónica, Ricardo Reges, David Cohen, Fabio Henrique da Silva, Gilberto De Nucci, [...]

DOI: 10.1590/S1679-45082010AO1789

ABSTRACT Objective: to evaluate the protective effects of BAY 41-2272, a soluble guanylate cyclase activator, on changes in cystometric parameters in rats deficient in nitric oxide (NO). Methods: Rats were divided into the following groups: (a) control; (b) DMSO; (c) L-NAME; (d) BAY 41-2272 alone; (e) L-NAME + BAY 41-2272. The NO synthase blocker L-NAME (20 mg/rat/day) was given in drinking water concomitantly or not with BAY 41-2272 (10 mg/kg/day, given by gavage). Results: Chronic L-NAME treatment markedly increased the […]

Correlation between urodynamic tests, history and clinical findings in treatment of women with urinary incontinence

João Bosco Ramos Borges, Telma Guarisi, Ana Carolina Marchesini de Camargo, Pítia Cárita de Godoy Borges

DOI: 10.1590/S1679-45082010AO1611

ABSTRACT Objective: The aim of this study was to evaluate the role of urodynamic test in diagnosis of urinary incontinence, comparing detailed data of history and physical examination, and some easy- to-apply clinical tests. Methods: A cross-sectional retrospective study was carried out by reviewing the medical charts of 55 patients with complaint of loss of urine, seen at the Urogynecology Service of Women’s Health Outpatient Clinic of Hospital Universitário de Jundiaí, between October 2006 and March 2007. The patients answered […]

Adductor pollicis muscle and hand grip strength: potential methods of nutritional assessment in outpatients with stroke

Débora Rocha Oliveira, Vera Silvia Frangella

DOI: 10.1590/S1679-45082010AO1763

ABSTRACT Objective: To evaluate and compare the effectiveness of different methods used for nutritional assessment of outpatients who had hemiplegic stroke. Methods: A cross-section study with adult and elderly patients of both genders enrolled in a rehabilitation center. The analyzed variables were anthropometric measurements, bioelectrical impedance, hand grip strength and thickness of the adductor pollicis muscle. The Pearson χ2 test was used to check the association between variables with a significance level of α = 5%. Results: When evaluating the […]

Amount of tobacco consumption is associated with superficial bladder cancer progression

Fernando Korkes, César Augusto Braz Juliano, Maria Alice Peluso Bunduky, Ana Carolina Duarte Martins Costa, Marilia Germanos de Castro

DOI: 10.1590/S1679-45082010AO1751

ABSTRACT Objective: To evaluate the association between smoking habits and outcome of patients with superficial bladder cancer. Methods: A retrospective study was performed evaluating 99 patients (67.0 ± 13.2 years, ranging from 31.4-93.4 years, 72.7% males and 27.3% females) treated at our institution with non muscle-invasive bladder cancer, between 1994 and 2000, with a mean follow-up of 49.3 months (range 4.0-177.9 months). Patients were divided according to smoking status, and the main measured outcome was progression to invasive disease. Additional […]

Congenital malformations in newborns of alcoholic mothers

Maria dos Anjos Mesquita, Conceição Aparecida de Mattos Segre

DOI: 10.1590/S1679-45082010AO1880

ABSTRACT Objective: To identify the presence of fetal alcohol syndrome, other alcohol-related congenital defects, and/or neurodevelopment disorders in newborns of mothers who consumed alcohol during gestation. Methods: In a public maternity in the city of São Paulo, 1,964 puerperal women were interviewed and 654 had consumed alcohol at some point during gestation. The newborns were clinically and laboratorially examined in order to identify the occurrence of fetal alcohol syndrome, congenital defects or neurodevelopment disorders related to alcohol. Results: Three children […]

A descriptive study of prostate cancer mortality in the state of São Paulo, from 1980 to 2007

Ary Serpa Neto, Marcos Tobias-Machado, Marcelo Langer Wroclawski, Marco Akerman, Antônio Carlos Lima Pompeo, Auro Del Giglio

DOI: 10.1590/S1679-45082010AO1707

ABSTRACT Objective: Prostate cancer is the second most common neoplasm among men worldwide. This study aimed to examine the trend in mortality rates of prostate cancer among the population in the state of São Paulo, Brazil, from 1980 to 2007. Methods: a descriptive study of temporal series was conducted using mortality data due to prostate cancer between1980 and 2007 in the state of São Paulo. Mortality rates were obtained from the SUS Information System on Mortality (SIM/SUS – DATASUS). The […]

Diagnosis of growing pains in a Brazilian pediatric population: a prospective investigation

Luciana Pereira Almeida de Piano, Ricardo Prado Golmia, Andrea Pimentel Fonseca Golmia, Adriana Maluf Elias Sallum, Lucia Akemi Nukumizu, Damião Guedes Castro, [...]

DOI: 10.1590/S1679-45082010AO1692

ABSTRACT Objective: To establish the clinical aspects of growing pains and to determine, through differential diagnosis, how many patients who referred themselves to a specialized clinic were found to have growing pains. Methods: This study prospectively examined the presence of growing pains in a self-reported population of children and adolescents with signs and symptoms (lower limb pains) of unexplained etiology. Results: A total of 345 children and adolescents were evaluated; 174 (50.4%) were males and 171 (49.6%) were females. Three […]

Sexuality in women with polycystic ovary syndrome: a pilot study

Jucilene Sales da Paixão Silva, Angela Maggio da Fonseca, Vicente Renato Bagnoli, Ana Lucia Cavalcanti, José Maria Soares Jr, Edmund Chada Baracat

DOI: 10.1590/S1679-45082010AO1836

ABSTRACT Objective: The objective of this study was to evaluate the sexual behavior of women with polycystic ovary syndrome and the relationship between sexual behavior and the clinical parameters related to this syndrome (obesity, hirsutism and menstrual irregularities). Methods: A cross-sectional study was carried out involving 48 women with polycystic ovary syndrome. The evaluation was based on the complaints reported by the women with particular emphasis on sexual satisfaction, the presence of a sexual partner, phases of the sexual response […]

Physical activity and stress coping in the elderly

Fernando de Andréa, Fernanda Varkala Lanuez, Adriana Nunes Machado, Wilson Jacob Filho

DOI: 10.1590/S1679-45082010AO1549

ABSTRACT Objective: To analyze the value of a physical activity program on stress coping of the elderly. Methods: Intervention study with a group of 18 elderly people referred by the Geriatric Service of the Hospital das Clinicas of the Universidade de Sao Paulo, who attended a supervised exercise program, evaluated by the human activity profile and the coping questionnaire. Results: In the coping and functional performance scales, increased stress coping capacity and improvement of daily activities were found after exposure […]

Evaluation of semen parameters in semen donors in a ten-year period in the city of São Paulo

Sidney Glina, Thiago Nova, Vera Beatriz Fehér Brand, Erica Molina, Andrea Giannotti Galuppo, Nadeje Regina Correa, [...]

DOI: 10.1590/S1679-45082010AO1546

ABSTRACT Objective: To evaluate sperm concentration, morphology and motility of Brazilian semen donors from 1992 to 2003, in the city of São Paulo. Methods: Retrospective study analyzing 182 donor semen samples from 1992 to 2003. The first and the second donated sample were analyzed for each donor. Donor average age was 30.8 years. Means with standard errors, medians with minimum and maximum values, and interquartile ranges were calculated for age, sperm concentration, semen volume, oval morphology and motility. The relation […]

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