557 results

Assessing how emergency and trauma ultrasonography is taught to medical students

José Cruvinel Neto ORCID logo , Vinicius Rinaldi Vieira Marcondes ORCID logo , Marcelo Augusto Fontenelle Ribeiro Junior ORCID logo

DOI: 10.31744/einstein_journal/2019AO4469

ABSTRACT Objective To evaluate a method aimed at teaching ultrasound techniques to medical students in emergency settings. Methods A prospective study conducted with 66 sixth-year undergraduate medical students. Students participated in theory and practicing sessions with a 5-hour load; knowledge acquisition was assessed through pre- and post-course and 90-day tests. A questionnaire were distributed to the students after course completion for theoretical and practical knowledge assessment. Results Average pre-test grade in theoretical content evaluation was 4.9, compared to 7.6 right […]

Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors

Valeria de Freitas Dutra ORCID logo , Carolina Bonet Bub ORCID logo , Thiago Henrique Costa ORCID logo , Leandro Dinalli Santos ORCID logo , Eduardo Peres Bastos ORCID logo , Maria Giselda Aravechia ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4477

ABSTRACT Objective To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood. Methods We included 867 healthy unrelated volunteer donors who donated platelets between January 2011 and December 2014. Microarray genotyping was performed using a BeadChip microarray. Medium resolution typing of the human leukocyte antigen at loci A and B was carried out using sequence-specific […]

Association between respiratory capacity, quality of life and cognitive function in elderly individuals

Rayana de Oliveira Costa ORCID logo , Raphael Mendes Ritti-Dias ORCID logo , Gabriel Grizzo Cucato ORCID logo , Maysa Seabra Cendoroglo ORCID logo , Fabio Nasri ORCID logo , Maria Luiza Monteiro Costa ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4337

ABSTRACT Objective To investigate associations between respiratory capacity, quality of life and cognitive function in elderly individuals. Methods The sample included 386 elderly individuals (232 women). Respiratory capacity assessment was based on maximal expiratory pressure measured at peak expiratory flow. Subjects were classified according to peak expiratory flow values adjusted for sex, age and height of individuals with normal (peak expiratory flow curve 60%) or reduced (peak expiratory flow curve < 60%) respiratory capacity. The World Health Organization Quality of [...]

Streptococcus mutans detection in saliva and colostrum samples

Camilla Beatriz da Silva ORCID logo , Marcelly Milhomem Mendes ORCID logo , Bárbara Rocha Rodrigues ORCID logo , Thiago Lima Pereira ORCID logo , Denise Bertulucci Rocha Rodrigues ORCID logo , Virmondes Rodrigues Junior ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4515

ABSTRACT Objective To detect Streptococcus mutans in colostrum and saliva of neonates and compare with its detection in saliva of mothers. Methods Forty-three healthy women, full-term gestations with no complications, submitted to elective Cesarean section, and their newborns were included in the study. Samples were investigated by polymerase chain reaction to detect S. mutans in genetic material from the samples. Results Approximately 16% of colostrum samples showed S. mutans , but not correlated with the presence of the bacteria in […]

Hormone receptor-negative as a predictive factor for pathologic complete response to neoadjuvant therapy in breast cancer

Luana Carolina Ferreira Fiuza Silva ORCID logo , Lilian Silva Martins de Arruda ORCID logo , Waldec Jorge David Filho ORCID logo , Felipe José Silva Melo Cruz ORCID logo , Damila Cristina Trufelli ORCID logo , Auro del Giglio ORCID logo

DOI: 10.31744/einstein_journal/2019AO3434

ABSTRACT Objective To define a predictive factor for pathologic complete response, compare the oncologic outcomes associated with the degree of pathologic response after neoadjuvant chemotherapy, and to analyze pathologic complete response as a prognostic factor for overall survival and progression-free survival. Methods A retrospective study of patients admitted to Hospital Estadual Mário Covas and Hospital Anchieta from 2008 to 2012, with locally advanced breast cancer. Hormone receptor status, HER2 status, histologic and nuclear grade, age upon diagnosis and histological type […]

Prevalence of G6PD deficiency and molecular characterization of G202A, A376G and C563T polymorphisms in newborns in Southeastern Brazil

Lucas Luís Meigre Dias Pereira ORCID logo , Cristina Augusta Bravin ORCID logo , Terezinha Sarquis Cintra ORCID logo , Wélida Santos Portela Cassa ORCID logo , Thainá Altoé Santos ORCID logo , Armando Fonseca ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4436

ABSTRACT Objective To evaluate the prevalence of G6PD deficiency and characterize G202A, A376G and C563T polymorphisms in neonates using molecular assays. Methods A total of one thousand samples were tested through quantitative analysis of enzyme activity, detecting 25 G6PD-deficient individuals. Patients identified as deficient were submitted to molecular analysis quantitative real-time polymerase chain reaction – (qPCR) to investigate the presence of variants associated with the deficiency. Results The total prevalence of G6PD deficient was 2.5%. Of the 25 samples identified […]

Influence of parental smoking on the use of alcohol and illicit drugs among adolescents

Luciano Machado Ferreira Tenório de Oliveira ORCID logo , Ana Raquel Mendes dos Santos ORCID logo , Breno Quintella Farah ORCID logo , Raphael Mendes Ritti-Dias ORCID logo , Clara Maria Silvestre Monteiro de Freitas ORCID logo , Paula Rejane Beserra Diniz ORCID logo

DOI: 10.31744/einstein_journal/2019AO4377

ABSTRACT Objective: To evaluate the association between parental smoking and the use of alcohol and illicit drugs among adolescent children. Methods: A cross-sectional study with 6,264 adolescents (59.7% female) aged between 14 and 19 years. To establish the sample, we used two-stage cluster random sampling. The data on parental smoking and use of cigarettes, alcohol and illicit drugs among adolescents were collected using a questionnaire. Results: Smoking adolescents were more prone to use alcohol (odds ratio − OR: 10.35; 95%CI: […]

Comparison of the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in normoglycemic and hyperglycemic subjects

Brena Barros Mendes ORCID logo , Anniely Carvalho Rebouças Oliveira ORCID logo , Keila Correia de Alcântara ORCID logo

DOI: 10.31744/einstein_journal/2019AO4403

ABSTRACT Objective: To compare the neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as possible parameters of systemic inflammation in hyperglycemic and normoglycemic subjects. Methods: A retrospective, cross-sectional study of data collected from patients tested for fasting blood glucose, glycated hemoglobin (HbA1c) and blood count on the same day, between July and December 2016. Patients were divided into hyperglycemic and normoglycemic, and matched by age and sex. The data were analyzed using Epi Info™, version 7.2.1.0, for the Windows® platform. Results: We enrolled 278 […]

Effects of overnight fasting on handgrip strength in inpatients

Wesley Santana Correa-Arruda ORCID logo , Iara dos Anjos Vaez ORCID logo , José Eduardo Aguilar-Nascimento ORCID logo , Diana Borges Dock-Nascimento ORCID logo

DOI: 10.31744/einstein_journal/2019AO4418

ABSTRACT Objective: To investigate the effects of overnight fasting on handgrip strength of adult inpatients. Methods: A prospective clinical study enrolling 221 adult patients. The endpoints were handgrip strength obtained by dynamometry in three time points (morning after an overnight fasting, after breakfast and after lunch) and the cumulative handgrip strength (mean of handgrip strength after breakfast and lunch) in the same day. The mean of three handgrip strength measures was considered to represent each time point. A cut-off for […]

When color helps

Ana Luiza Fontes de Azevedo Costa ORCID logo , Thiago Gonçalves dos Santos Martins ORCID logo , Ricardo Vieira Martins ORCID logo , Paulo Schor ORCID logo

DOI: 10.31744/einstein_journal/2019AO4410

ABSTRACT Objective: To reduce the inappropriate identification of eye drops, through the use of different colors. Methods: A group of 34 healthy volunteers was presented to two groups of four eye drops each. All eye drops were placed in identical, unlabelled vials. In one group, all four eye drops were transparent. In the other group, each had a different color. A number was assigned to each eye drop, and the volunteer was asked to identify it by color. We measured […]

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