557 results

Experimental study for evaluation of a low-cost spray cryotherapy system

Altair da Silva Costa Jr ORCID logo , Andre Miotto ORCID logo , Gustavo Andrade de Paulo ORCID logo , Angelo Paulo Ferrari ORCID logo , Luiz Hirotoshi Ota ORCID logo

DOI: 10.31744/einstein_journal/2019AO4533

ABSTRACT Objective To evaluate the feasibility and applicability of a low-cost cryotherapy system. Methods Experimental study with 25kg Landrace pigs submitted to a longitudinal cervico-thoraco-abdominal incision for exposure of the trachea, thorax and abdomen. The tissues were frozen by continuous spray application at different periods of time (5, 10 and 15 seconds). Spray cryotherapy was performed using a fluorinated gas (tetrafluorethane) delivered at – 47°C temperature (DermaFreeze®, Emdutos; ANVISA registration 80409950001; price R$ 394,00). via an adapted, disposable 1.8mm cholangiography […]

Development of a Brazilian anticholinergic activity drug scale

Raiany Thaimeny Nery ORCID logo , Adriano Max Moreira Reis ORCID logo

DOI: 10.31744/einstein_journal/2019AO4435

ABSTRACT Objective To develop a scale of anticholinergic activity drugs used in Brazil, to be applied in health care and pharmacoepidemiology research. Methods We performed a literature review on PubMed/MEDLINE® to identify previously published scales of anticholinergic drugs. This scale started with anticholinergic drugs, and those with known anticholinergic activity as per the 4th level, chemical-therapeutic subgroup, of the Anatomical Therapeutic Chemical classification. We also included drugs with high anticholinergic activity, as described in a list of potentially inappropriate medications […]

Electrocardiographic changes in spondyloarthritis and use of anti-TNF-α drugs: a retrospective study with 100 patients

Betânia Longo ORCID logo , Luziel Andrei Kirchner ORCID logo , Juliana Simioni ORCID logo , Ana Paula Beckhauser de Campos ORCID logo , Thelma Larocca Skare ORCID logo

DOI: 10.31744/einstein_journal/2019AO4539

ABSTRACT Objective To investigate the prevalence of electrocardiographic changes in patients with spondyloarthritis and to correlate these changes with use of anti-tumor necrosis factor-alpha (TNF-α) drugs and HLA-B27 positivity. Methods Retrospective study including 100 patients diagnosed with spondyloarthritis according to Assessment of SpondyloArthritis International Society (ASAS) criteria and 50 controls. Epidemiological and clinical features, results of inflammatory activity tests, HLA-B27 positivity, and medication use data were extracted from medical records. Disease activity was assessed using the Bath Ankylosing Spondylitis Disease […]

Development and clinical validation of a non-invasive, beat-to-beat blood pressure monitoring device, compared to invasive blood pressure monitoring during coronary angiography

Melania Aparecida Borges ORCID logo , Marcelo Prado ORCID logo , Tales Roberto de Souza Santini ORCID logo , Adriano Henrique Pereira Barbosa ORCID logo , Antonio Carlos Moreira ORCID logo , Eder Issao Ishibe ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4156

ABSTRACT Objective To develop and test a beat-to-beat blood pressure monitoring device during coronary angiography, and compare it with invasive blood pressure monitoring. Methods Twenty-eight patients with an indication for hemodynamic study were selected for this investigation, and kept in supine position. Before starting the coronary angiography, they were instructed about the use of the left radial bracelet for beat-to-beat blood pressure monitoring. Results There was a significant difference between the time required for the catheterization laboratory team to acquire […]

Training in recovery, perfusion and packaging of organs for transplants: profile of professionals and analysis of post-course learning

Juliana Guareschi dos Santos ORCID logo , Veronica Schonfeld Gomes Silva ORCID logo , Luciana Cintra ORCID logo , Cassiane Dezoti da Fonseca ORCID logo , Luciana Carvalho Moura Tralli ORCID logo

DOI: 10.31744/einstein_journal/2019AO4445

ABSTRACT Objective To understand the profile of professionals working in organ harvesting, and analyze the learning results of those trained before and after the course on recovery, perfusion and packaging of organs for transplants. Methods A retroprospective, quantitative, analytical-descriptive study about the Course on Recovery, Perfusion and Packaging of Liver and Kidney, in the period from 2012 to 2014. Pre- and post-tests, with ten questions were used to assess knowledge about organ harvesting. The association of knowledge with applied content […]

Water protection in patients with tympanostomy tubes in tympanic membrane: a randomized clinical trial

Marcel Menon Miyake ORCID logo , Daniela Akemi Tateno ORCID logo , Natália Amaral Cançado ORCID logo , Michelle Menon Miyake ORCID logo , Stefano Tincani ORCID logo , Osmar Mesquita de Sousa Neto ORCID logo

DOI: 10.31744/einstein_journal/2019AO4423

ABSTRACT Objective To analyze the incidence of otorrhea in the postoperative period of patients submitted to tympanotomy to place ventilation tube, and who did not protect the ear when exposed to water. Methods Open, randomized-controlled trial. Eighty patients submitted to unilateral or bilateral ear grommet tympanostomy were included and divided into two groups: Auricular Protection and Non-Protection to water during bathing and activities in water. Results In the first postoperative month, the Non-Protection Group presented a significant increase in the […]

Risk factors associated with in-hospital falls reported to the Patient Safety Commitee of a teaching hospital

Adriane Kênia Moreira Silva ORCID logo , Dayane Carlos Mota da Costa ORCID logo , Adriano Max Moreira Reis ORCID logo

DOI: 10.31744/einstein_journal/2019AO4432

ABSTRACT Objective To investigate the use of fall-risk-increasing drugs among patients with falls reported to the Patient Safety Office of a hospital, and to identify the factors associated with high risk for fall. Methods A cross-sectional study, carried out in a teaching hospital. The study population was the universe of fall reports received by the Patient Safety Office. The dependent variable was a high risk for falls. The Medication Fall Risk Score was used to measure fall risk. Descriptive, univariate […]

Near-infrared spectroscopy parameters in patients undergoing continuous venovenous hemodiafiltration

Renato Carneiro de Freitas Chaves ORCID logo , Philipe Franco do Amaral Tafner ORCID logo , Felipe Ko Chen ORCID logo , Letícia Bagatini Meneghini ORCID logo , Thiago Domingos Corrêa ORCID logo , Roberto Rabello Filho ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4439

ABSTRACT Objective To investigate the impacts of continuous venovenous hemodiafiltration on the microcirculation in patients with acute kidney injury. Methods A prospective observational pilot study conducted in a 40-bed, open clinical-surgical intensive care unit of a private tertiary care hospital located in the city of São Paulo (SP), Brazil. Microcirculation was assessed using near-infrared spectroscopy by means of a 15mm probe placed over the thenar eminence. Vascular occlusion test was performed on the forearm to be submitted to near-infrared spectroscopy […]

Effective vancomycin concentrations in children: a cross-sectional study

Geisa Cristina da Silva Alves ORCID logo , Farah Maria Drumond Chequer ORCID logo , Cristina Sanches ORCID logo

DOI: 10.31744/einstein_journal/2019AO4396

ABSTRACT Objective Analyze the microbiological effectiveness, based on the pharmacokinetics/pharmacodynamics correlation of vancomycin in pediatric patients, and to propose dose adjustment. Methods This is an observational, cross-sectional study, conducted in a pediatric hospital, over a 1-year period (2016 to 2017). Children of both sexes, aged 2 to 12 years, were included in the study; burn children, and children in renal replacement therapy were excluded. For the pharmacokinetic analysis, two samples of 2mL of whole blood were collected, respecting the 2-hour […]

Evaluation of the quality of Primary Health Care services for children: reflections on the feasibility of using the Brazilian version of the Primary Care Assessment Tool as a routine assessment tool

Liz Ponnet ORCID logo , Sara Willems ORCID logo , Veerle Vyncke ORCID logo , Aylene Emilia Moraes Bousquat ORCID logo , Ana Luiza d’Ávila Viana ORCID logo , Guilherme Arantes Mello ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4333

ABSTRACT Objective To assess the quality of the Primary Health Care services provided to children and the feasibility of using the Brazilian version of Primary Care Assessment Tool (PCAT-Brazil) as a routine quality assessment tool. Methods A cross-sectional study was carried out in Joanópolis, a small rural town in the State of São Paulo (SP), Brazil. Seven health professionals and 502 caretakers of children using the public health center were interviewed using the PCAT-Brazil, collecting data on the core and […]

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