12 results

Role of adipose tissue-derived stem cells in the progression of renal disease

Cassiano Donizetti-Oliveira, Patricia Semedo, Marina Burgos-Silva, Marco Antonio Cenedeze, Denise Maria Avancini Costa Malheiros, Marlene Antônia dos Reis, [...]

DOI: 10.1590/S1679-45082011AO1833

ABSTRACT Objective: To analyze the role of adipose tissue-derived stem cells in reducing the progression of renal fibrosis. Methods: adipose tissue-derived stem cells were isolated from C57Bl/6 mice and characterized by cytometry and differentiation. Renal fibrosis was established after unilateral clamping of the renal pedicle for 1 hour. Four hours after reperfusion, 2.105 adipose tissue-derived stem cells were administered intraperitoneally and the animals were followed for 24 hours during 6 weeks. In another experimental group, 2.105 adipose tissue-derived stem cells […]

Effects of dietary fiber intake on inflammation in chronic diseases

Ana Maria Pita Lottenberg, Patricia Luriko Tomita Fan, Vivian Buonacorso

DOI: 10.1590/s1679-45082010md1310

ABSTRACTChronic diseases such as obesity, type-2 diabetes, metabolic syndrome and cardiovascular diseases are associated with inflammation due the increase of TNF-α, IL-6 and C-reactive protein concentrations. Occidental life style, specially related to the changes in food habits as observed in the past years, have an important role in the development of these diseases. Among the life style changes identified as having an impact in the development of diseases, is the decrease in dietary fiber consumption. Some studies have shown the […]

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