All publications of “Roberto Ferreira Meirelles Junior”

4 results

Pancreas transplantation: review

Roberto Ferreira Meirelles Júnior, Paolo Salvalaggio, Alvaro Pacheco-Silva

DOI: 10.1590/S1679-45082015RW3163

ABSTRACTVascularized pancreas transplantation is the only treatment that establishes normal glucose levels and normalizes glycosylated hemoglobin levels in type 1 diabetic patients. The first vascularized pancreas transplant was performed by William Kelly and Richard Lillehei, to treat a type 1 diabetes patient, in December 1966. In Brazil, Edison Teixeira performed the first isolated segmental pancreas transplant in 1968. Until the 1980s, pancreas transplants were restricted to a few centers of the United States and Europe. The introduction of tacrolimus and […]

Liver transplantation: history, outcomes and perspectives

Roberto Ferreira Meirelles Júnior, Paolo Salvalaggio, Marcelo Bruno de Rezende, Andréia Silva Evangelista, Bianca Della Guardia, Celso Eduardo Lourenço Matielo, [...]

DOI: 10.1590/S1679-45082015RW3164

In 1958 Francis Moore described the orthotopic liver transplantation technique in dogs. In 1963, Starzl et al. performed the first liver transplantation. In the first five liver transplantations no patient survived more than 23 days. In 1967, stimulated by Calne who used antilymphocytic serum, Starzl began a successful series of liver transplantation. Until 1977, 200 liver transplantations were performed in the world. In that period, technical problems were overcome. Roy Calne, in 1979, used the first time cyclosporine in two […]

Intestinal and multivisceral transplantation

Sérgio Paiva Meira Filho, Bianca Della Guardia, Andréia Silva Evangelista, Celso Eduardo Lourenço Matielo, Douglas Bastos Neves, Fernando Luis Pandullo, [...]

DOI: 10.1590/S1679-45082015RW3155

Intestinal transplantation has shown exceptional growth over the past 10 years. At the end of the 1990’s, intestinal transplantation moved out of the experimental realm to become a routine practice in treating patients with severe complications related to total parenteral nutrition and intestinal failure. In the last years, several centers reported an increasing improvement in survival outcomes (about 80%), during the first 12 months after surgery, but long-term survival is still a challenge. Several advances led to clinical application of […]

Pancreas transplantation: an overview

Andre Ibrahim David, Ben-Hur Ferraz-Neto, Fernando Levino, Roberto Ferreira Meirelles Junior, Álvaro Pacheco e Silva Filho

DOI: 10.1590/S1679-45082010MD1716

ABSTRACT Pancreas transplantation is the only treatment able to reestablish normal glucose and glycated hemoglobin levels in insulin-dependent diabetic patients without the use of exogenous insulin. The evolution of pancreas transplantation in treatment of diabetes was determined by advances in the fields of surgical technique, organ preservation and immunosuppressants. The main complication leading to graft loss is technical failure followed by acute or chronic rejection. Technical failure means graft loss within the first three months following transplantation due to vascular […]