All publications of “Luciano Miller Reis Rodrigues”

6 results

Inflammatory biomarkers in sera of patients with intervertebral disc degeneration

Luciano Miller Reis Rodrigues ORCID logo , Lilian Zerbinatti de Oliveira ORCID logo , Mariane de Barros Ribeiro da Silva ORCID logo , Camila de Melo Accardo ORCID logo , Adriana Braz Del Giglio ORCID logo , Maria Aparecida da Silva Pinhal ORCID logo

DOI: 10.31744/einstein_journal/2019AO4637

ABSTRACT Objective: To evaluate intervertebral disc levels of inflammatory factor (interleukin 6) and proteinase activity (cathepsin B) in patients with a degenerative disease and serum levels of interleukin 6, serum cathepsin B activity and hyaluronic acid biomarkers. Methods: We conducted immunohistochemistry studies of intervertebral discs to analyze interleukin 6 and cathepsin B levels of patients with degenerative disease and spine fracture (Control Group) and to measure hyaluronic acid, interleukin 6 and cathepsin B activity from sera of intervertebral disc degeneration […]

Vascular endothelial growth factor gene variations as a risk predictor in disc degeneration

Aline Amaro, Ana Beatriz Guerra, Matheus Pippa Defino, Luiz Angelo Vieira, Carla Peluso, Bianca Bianco, [...]

DOI: 10.1590/S1679-45082017AO4053

ABSTRACT Objective: To evaluate the frequency of polymorphisms in the vascular endothelial growth factor (VEGF) gene, as well as to identify a potential risk haplotype among the polymorphic regions in this gene in patients with disc degeneration and in the Control Group. Methods: This study analyzed a total of 217 individuals distributed into the Disc Degeneration and Control Groups. Peripheral blood was collected from all patients to detect VEGF gene polymorphisms identified by qPCR (rs699947, rs1570360, rs2010963, rs833061 and rs3025039). […]

Histological analysis of the repair of dural lesions with silicone mesh in rats subjected to experimental lesions

Fernando William Figueiredo da Rosa, Pedro Henrique Isoldi Pohl, Ana Maria Amaral Antônio Mader, Carla Peluso de Paiva, Aline Amaro dos Santos, Bianca Bianco, [...]

DOI: 10.1590/S1679-45082015AO3378

ABSTRACTObjective To evaluate inflammatory reaction, fibrosis and neovascularization in dural repairs in Wistar rats using four techniques: simple suture, bovine collagen membrane, silicon mesh and silicon mesh with suture.Methods Thirty Wistar rats were randomized in five groups: the first was the control group, submitted to dural tear only. The others underwent durotomy and simple suture, bovine collagen membrane, silicon mesh and silicon mesh with suture. Animals were euthanized and the spine was submitted to histological evaluation with a score system […]

Reliability analysis of radiographic methods for determination of posterolateral lumbossacral fusion

Alberto Ofenhejm Gotfryd, Felipe de Moraes Pomar, Nicola Jorge Carneiro Neto, Fernando José Franzin, Luciano Miller Reis Rodrigues, Patricia Rios Poletto

DOI: 10.1590/S1679-45082014AO2964

ObjectiveTo analyze intra and interobserver agreement of two radiographic methods for evaluation of posterolateral lumbar arthrodesis.MethodsTwenty patients undergoing instrumented posterolateral fusion were evaluated by anteroposterior and dynamic lateral radiographs in maximal flexion and extension. The images were evaluated initially by 6 orthopedic surgeons, and after 8 weeks, reassessed by 4 of them, totaling 400 radiographic measurements. Intra and interobserver reliability were analyzed using the Kappa coefficient and Landis and Koch criteria.ResultsIntra and interobserver agreement regarding anteroposterior radiographs were, respectively, 76 […]

Herniated lumbar disc surgery in triathlon athletes with intraoperative neurophysiologic monitoring

Luciano Miller Reis Rodrigues, Fernando William Figueiredo da Rosa, Ricardo Jose Rodriguez Ferreira, Fabrício Ueno, Carlo Milani

DOI: 10.1590/s1679-45082011rc1947

ABSTRACTIntraoperative neurophysiologic monitoring was performed in a patient by somatosensory evoked potential, motor evoked potential and free-running electromyography with intraoperative stimulation. It was verified that after decompression, there was an increase in the amplitude of motor evoked potential responses, showing an immediate improvement of the treated levels. Intraoperative neurophysiologic monitoring for surgical lumbar disc herniation in an athlete allowed a dynamic neurophysiological diagnosis, differentiation of the involvement of compression at the central or foraminal levels, and clinical awareness of the […]