All publications of “Bárbara de Souza Gutierres”

3 results

Cost-effectiveness analysis of abiraterone, docetaxel or placebo plus androgen deprivation therapy for hormone-sensitive advanced prostate cancer

Pedro Nazareth Aguiar Jr. ORCID logo , Pui San Tan ORCID logo , Sarah Simko ORCID logo , Carmelia Maria Noia Barreto ORCID logo , Bárbara de Souza Gutierres ORCID logo , Auro del Giglio ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019GS4414

ABSTRACT Objective To evaluate the cost-effectiveness of the addition of chemotherapy or abiraterone to androgen deprivation. Methods We developed an analytical model to determine the cost-effectiveness of the addition of docetaxel or abiraterone versus androgen deprivation therapy alone. Direct and indirect costs were included in the model. The effects were expressed in Quality-Adjusted Life Years adjusted for side effects. Results Compared to androgen deprivation therapy alone, the addition of chemotherapy and of abiraterone generated 0.492 and 0.999, respectively, in Quality-Adjusted […]

Cost effectiveness of chemohormonal therapy in patients with metastatic hormone-sensitive and non-metastatic high-risk prostate cancer

Pedro Nazareth Aguiar Jr., Carmélia Maria Noia Barreto, Bárbara de Souza Gutierres, Hakaru Tadokoro, Gilberto de Lima Lopes Jr

DOI: 10.1590/S1679-45082017GS4017

ABSTRACT Objective To assess the cost-effectiveness of chemohormonal therapy in patients with metastatic hormone-sensitive and non-metastatic high-risk prostate cancer. Methods An analytical decision model was developed to determine the cost-effectiveness of chemohormonal therapy versus androgen deprivation therapy alone in patients with metastatic hormone-sensitive prostate cancer and patients with non-metastatic high-risk prostate cancer. The cost-effectiveness in metastatic patients with a high-volume disease was assessed separately. The model used data from randomized clinical trials and drug acquisition costs in Brazil. In addition, […]

Disparities in cancer epidemiology and care delivery among Brazilian indigenous populations

Pedro Nazareth Aguiar Jr., Gustavo Trautman Stock, Gilberto de Lima Lopes Jr., Michelle Samora de Almeida, Hakaru Tadokoro, Bárbara de Souza Gutierres, [...]

DOI: 10.1590/S1679-45082016AO3754

ABSTRACTObjective:To assess aspects related to cancer in indigenous population.Methods:This is a retrospective study developed in a public university hospital. We included patients with 18 or more years of age, diagnosed with solid tumors, and followed between 2005 and 2015. Clinical features were assessed by descriptive statistics, and survival was evaluated by Kaplan-Meier curves and multivariate Cox regression.Results:Fifty patients were included. The cancer incidence was 15.73 per 100,000. The mean age at diagnosis was 54 years and most patients were female […]