All publications of “Auro Del Giglio”

17 results

Cost-effectiveness analysis of abiraterone, docetaxel or placebo plus androgen deprivation therapy for hormone-sensitive advanced prostate cancer

Pedro Nazareth Aguiar Jr. ORCID logo , Pui San Tan ORCID logo , Sarah Simko ORCID logo , Carmelia Maria Noia Barreto ORCID logo , Bárbara de Souza Gutierres ORCID logo , Auro del Giglio ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019GS4414

ABSTRACT Objective To evaluate the cost-effectiveness of the addition of chemotherapy or abiraterone to androgen deprivation. Methods We developed an analytical model to determine the cost-effectiveness of the addition of docetaxel or abiraterone versus androgen deprivation therapy alone. Direct and indirect costs were included in the model. The effects were expressed in Quality-Adjusted Life Years adjusted for side effects. Results Compared to androgen deprivation therapy alone, the addition of chemotherapy and of abiraterone generated 0.492 and 0.999, respectively, in Quality-Adjusted […]

Hormone receptor-negative as a predictive factor for pathologic complete response to neoadjuvant therapy in breast cancer

Luana Carolina Ferreira Fiuza Silva ORCID logo , Lilian Silva Martins de Arruda ORCID logo , Waldec Jorge David Filho ORCID logo , Felipe José Silva Melo Cruz ORCID logo , Damila Cristina Trufelli ORCID logo , Auro del Giglio ORCID logo

DOI: 10.31744/einstein_journal/2019AO3434

ABSTRACT Objective To define a predictive factor for pathologic complete response, compare the oncologic outcomes associated with the degree of pathologic response after neoadjuvant chemotherapy, and to analyze pathologic complete response as a prognostic factor for overall survival and progression-free survival. Methods A retrospective study of patients admitted to Hospital Estadual Mário Covas and Hospital Anchieta from 2008 to 2012, with locally advanced breast cancer. Hormone receptor status, HER2 status, histologic and nuclear grade, age upon diagnosis and histological type […]

Clinical features and overall survival among elderly cancer patients in a tertiary cancer center

Yuri Philippe Pimentel Vieira Antunes, Diogo Diniz Gomes Bugano, Auro del Giglio, Rafael Aliosha Kaliks, Theodora Karnakis, Lucíola de Barros Pontes

DOI: 10.1590/S1679-45082015AO3067

ABSTRACTObjective To evaluate the epidemiological profile and overall survival of a large population of elderly individuals diagnosed with solid tumors in a tertiary hospital.Methods This retrospective study included patients aged >65 years, diagnosed with solid tumors between January 2007 and December 2011, at Hospital Israelita Albert Einstein, São Paulo, Brazil. The medical records were reviewed to obtain information about clinical variables and overall survival.Results A total of 806 patients were identified, and 58.4% were male. Mean age was 74 years […]

Assessment of adherence to the guidelines for the management of nausea and vomiting induced by chemotherapy

Monique Sedlmaier França, Pedro Luiz Serrano Usón Junior, Yuri Philippe Pimentel Vieira Antunes, Bernard Lobato Prado, Carlos del Cistia Donnarumma, Taciana Sousa Mutão, [...]

DOI: 10.1590/S1679-45082015AO3097

ABSTRACTObjective:To assess adherence of the prescribing physicians in a private cancer care center to the American Society of Clinical Oncology guideline for antiemetic prophylaxis, in the first cycle of antineoplastic chemotherapy.Methods:A total of 139 chemotherapy regimens, of 105 patients, were evaluated retrospectively from 2011 to 2013.Results:We observed 78% of non-adherence to the guideline rate. The main disagreements with the directive were the prescription of higher doses of dexamethasone and excessive use of 5-HT3 antagonist for low risk emetogenic chemotherapy regimens. […]

From one side to the other: what is essential? Perception of oncology patients and their caregivers in the beginning of oncology treatment and in palliative care

Bruna Antenussi Munhoz, Henrique Soares Paiva, Beatrice Martinez Zugaib Abdalla, Guilherme Zaremba, Andressa Macedo Paiva Rodrigues, Mayra Ribeiro Carretti, [...]

DOI: 10.1590/S1679-45082014RC3091

ObjectiveTo evaluate the perception of oncology patients and their caregivers upon diagnosis and beginning of the therapy and during palliative care.MethodsA cross-sectional study at the oncology and palliative care outpatients clinics of the Faculdade de Medicina do ABC. Clinical and demographic data from patients and their caregivers were collected and questionnaires regarding the elements considered important in relation to the treatment were applied.ResultsWe enrolled 32 patients and 23 caregivers that were initiating treatment at the oncology outpatient clinic, as well […]

Prevalence of renal insufficiency in elderly cancer patients in a tertiary cancer center

Lucíola de Barros Pontes, Yuri Philippe Pimentel Vieira Antunes, Diogo Diniz Gomes Bugano, Theodora Karnakis, Auro del Giglio, Rafael Aliosha Kaliks

DOI: 10.1590/s1679-45082014ao3003

Objective To estimate the prevalence of abnormal glomerular filtration rate in elderly patients with solid tumors.Methods A retrospective study with patients aged >65 years diagnosed with solid tumors between January 2007 and December 2011 in a cancer center. The following data were collected: sex, age, serum creatinine at the time of diagnosis and type of tumor. Renal function was calculated using abbreviated Modification of Diet in Renal Disease (MDRD) formulae and then staged in accordance with the clinical practice guidelines […]

Paullinia cupana for control of hot flashes in breast cancer patients: a pilot study

Saulo Silva Oliveira, Adriana Braz del Giglio, Tatiana Goberstein Lerner, Rebecca Melo Zanellato, Livia Tiemi, Lucas Reifur, [...]

DOI: 10.1590/S1679-45082013000400005

Objective:To evaluated whether Paullinia cupana decrease number and severity of hot flashes in breast cancer survivors.METHODS:This was a prospective phase II pilot study. We studied female breast cancer survivors who had completed the cancer treatment 3 months previously and who were experiencing at least 14 hot flashes per week. At least 9 of the 15 patients were required to have a decrease of at least 50% in hot flash severity score in keeping with the Simon Design. Patients received 50mg […]

Treatment of breast cancer patients from a public healthcare system in a private center: costs of care for a pilot public-private partnership in oncology

Rafael Aliosha Kaliks, Lucíola de Barros Pontes, Cinthia Leite Frizzera Borges Bognar, Kelly Cristine Carvalho Santos, Sílvio Eduardo Bromberg, Paulo Gustavo Tenório do Amaral, [...]

DOI: 10.1590/S1679-45082013000200014

Objective:To describe the flow and costs associated with the diagnosis and treatment of patients with breast cancer who come from the public healthcare system and were treated at Hospital Israelita Albert Einstein.METHODS:Between August 2009, and December 2011, 51 patients referred by the Unified Public Healthcare System (SUS) had access to Hospital Israelita Albert Einstein for diagnostic radiology, medical oncology, radiotherapy, and oncologic/breast reconstruction surgery. The data were collected retrospectively from the hospital records, patient charts, pharmacy records, and from the […]

Is there publication bias towards Brazilian articles on cancer?

Luiz Victor Maia Loureiro, Donato Callegaro Filho, Altieres de Arruda Rocha, Bernard Lobato Prado, Taciana Sousa Mutão, Carlos del Cistia Donnarumma, [...]

DOI: 10.1590/S1679-45082013000100005

Objective:To investigate whether Brazilian articles on cancer are published in journals with an impact factor and/or repercussion (measured by the number of citations) inferior to those that come from foreign organizations.METHODS:A search was carried out in PubMed for the MeSH term “neoplasm” with the limits clinical trial, affiliation of the Brazilian author(s), and interval from July 1st, 2009 to June 30, 2010. Selected for matching were non-Brazilian related articles published from three months prior to three months after the date […]

Multiple myeloma complicated with pseudomonas endocartiditis

Juliana Todaro, Patrícia Weinschenker Bollmann, Amit Nussbacher, Luis Fernando Aranha Camargo, Bento Fortunato Cardoso dos Santos, Daniel Alvarenga, [...]

DOI: 10.1590/S1679-45082012000400017

Patients diagnosed with multiple myeloma are more susceptible to infections which are the major causes of morbidity and mortality associated to this disease. The main infectious agents involved are Gram-positive bacteria. However, after chemotherapy an increase in the incidence of Gram-negative strains is observed. These bacteria are also responsible for most cases of urinary tract infections. Here is reported a rare case in a 73-year-old man with multiple myeloma who developed endocarditis due to pseudomonas.

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