All publications of “Alberto Goldenberg”

2 results

Higher overall survival in metastatic pancreatic cancer: the impact of where and how treatment is delivered

Pedro Luiz Serrano Usón Junior, Monique Sedlmaier França, Heloisa Veasey Rodrigues, Antônio Luiz de Vasconcellos Macedo, Alberto Goldenberg, Oren Smaletz, [...]

DOI: 10.1590/S1679-45082015AO3303

ObjectiveTo determine the overall survival of patients with advanced pancreatic cancer and evaluate factors that impact prognosis in a private cancer center.MethodsData from the Hospital Cancer Registry at Hospital Israelita Albert Einstein were retrospectively collected. The patients enrolled had metastatic cancer at diagnosis or earlier staging and subsequent recurrence. Cases of neuroendocrine tumors were excluded.ResultsA total of 65 patients were evaluated, including 63 with adenocarcinoma. The median overall survival for patients in all stages was 20.7 months (95%CI: 15.6-25.7), while […]

Expression of p53, p16 and Ki67 proteins in ductal adenocarcinoma of the pancreatic head and their relation with survival and cell differentiation

Mário Benjamin Goitia-Durán, Marcelo Moura Linhares, Ricardo Artigiani Neto, Franz Robert Apodaca-Torrez, Edson José Lobo, Alberto Goldenberg

DOI: 10.1590/S1679-45082010AO1655

ABSTRACT Objective: To determine the expression of p53, p16 and Ki-67 and its relevance in survival and cell differentiation. Methods: Fifteen duodenopancreatectomized patients were included. Immunohistochemical expression of p53, p16 and Ki-67 was determined in paraffin embedded tumor blocks. The relation of these expressions with different variables was studied. Results: Ninety-three per cent of tumors showed expression of p53 and p16. Ki-67 was expressed in 86.66% of tumors (labeling index – LI 11.91 ± 9.47). The presence of combined alterations […]