All publications of “Marilia Normanton”

2 results

Current data on IL-17 and Th17 cells and implications for graft versus host disease

Marília Normanton, Luciana Cavalheiro Marti

DOI: 10.1590/S1679-45082013000200019

Human interleukin 17 was first described in 1995 as a new cytokine produced primarily by activated T CD4+ cells that stimulate the secretion of IL-6 and IL-8 by human fibroblasts, besides increasing the expression of ICAM-1. Various authors have reported that IL-17A has a role in the protection of organisms against extracellular bacteria and fungi due to the capacity of IL-17A to recruit neutrophils to the areas of infection, evidencing a pathological role in various models of autoimmune diseases, such […]

Isolation and characterization of mesenchymal stem cells obtained from reusable and disposable bone marrow collection filters

Glaziane Cordeiro de Deus, Marilia Normanton, Nelson Hamerschlak, Andrea Tiemi Kondo, Andreza Alice Feitosa Ribeiro, Anna Carla Goldberg, [...]

DOI: 10.1590/S1679-45082012000300007

Objective:To compare human mesenchymal stem cells obtained from reusable and disposable filters and to characterize them according to the criteria of the International Society of Cellular Therapy.METHODS:Human mesenchymal stem cells were isolated from bone marrow collection reusable sets and compared with those obtained from disposable sets by washing the filters with cell culture media. The isolated cells were characterized according to the criteria of the International Society of Cellular Therapy using flow cytometry, differentiation in vitro, and cytochemistry techniques.RESULTS:Samples were […]