All publications of “Ilza Rosa Batista”

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SPEM: a state-of-the-art instrument for high resolution molecular imaging of small animal organs

Marilia Alves dos Reis, Jorge Mejia, Ilza Rosa Batista, Marycel Rosa Felisa Figols de Barboza, Solange Amorim Nogueira, Jairo Wagner, [...]

DOI: 10.1590/S1679-45082012000200015

Objective:To describe the Single Photon Emission Microscope (SPEM), a state-of-the-art instrument for small animal SPECT imaging, and characterize its performance presenting typical images of different animal organs.METHODS:SPEM consists of two independent imaging devices based on high resolution scintillators, high sensitivity and resolution Electron-Multiplying CCDs and multi-pinhole collimators. During image acquisition, the mouse is placed in a rotational vertical holder between the imaging devices. Subsequently, an appropriate software tool based on the Maximum Likelihood algorithm iteratively produces the volumetric image. Radiopharmaceuticals […]