All publications of “Dennys Esper Correa Cintra”

2 results

Obesity versus osteoarthritis: beyond the mechanical overload

Angélica Rossi Sartori-Cintra, Priscila Aikawa, Dennys Esper Correa Cintra

DOI: 10.1590/s1679-45082014rb2912

Obesity is currently considered a major public health problem in the world, already reaching epidemic characteristics, according to the World Health Organization. Excess weight is the major risk factor associated with various diseases, such as type 2 diabetes mellitus, hypertension, dyslipidemia and osteometabolic diseases, including osteoporosis and osteoarthritis. Osteoarthritis is the most prevalent rheumatic disease and the leading cause of physical disability and reduced quality of life of the population over 65 years. It mainly involves the joints that bear […]

Effects of different intensities of physical exercise on insulin sensitivity and protein kinase B/Akt activity in skeletal muscle of obese mice

Rodolfo Marinho, Leandro Pereira de Moura, Bárbara de Almeida Rodrigues, Luciana Santos Souza Pauli, Adelino Sanchez Ramos da Silva, Eloize Cristina Chiarreotto Ropelle, [...]

DOI: 10.1590/S1679-45082014AO2881

Objective:To investigate the effects of different intensities of acute exercise on insulin sensitivity and protein kinase B/Akt activity in skeletal muscle of obese mice.Methods: Swiss mice were randomly divided into four groups, and fed either a standard diet (control group) or high fat diet (obese sedentary group and obese exercise group 1 and 2) for 12 weeks. Two different exercise protocols were used: swimming for 1 hour with or without an overload of 5% body weight. The insulin tolerance test […]