All publications of “Alessandro Laviano”

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Sarcopenia and chemotherapy-mediated toxicity

Maria Cecília Monteiro Dela Vega, Alessandro Laviano, Gustavo Duarte Pimentel

DOI: 10.1590/s1679-45082016md3740

ABSTRACTThis narrative review focuses on the role of sarcopenia and chemotherapy-induced toxicity in cancer patients. Consistent evidence shows that sarcopenia in cancer patients leads to decreased overall survival by influencing treatment discontinuation and dose reduction. Therefore, sarcopenia should be considered a robust prognostic factor of negative outcome as well as a determinant of increased healthcare costs.