Recent Articles

einstein (São Paulo) an innovative way to publish your research

Edna Terezinha Rother

DOI: 10.1590/S1679-45082018ED4487

THE NEW MODEL OF PUBLISHING OF EINSTEIN (SÃO PAULO) Starting in 2018, (São Paulo) is moving to a new model of publishing, continuous publication. However, we will continue to produce, although at a reduced frequency, our print version. Our “ahead of print” model will no longer exist. This new model will bring a number of changes. The journal will have a new and user-friendly website to improve navigation and interoperability; in addition, continuous publication will enable immediate sharing of articles […]

Clinical and immunohistochemical study of melanotic neuroectodermal tumor of infancy in the maxilla

Hellen Bandeira de Pontes Santos, Aníbal Henrique Barbosa de Luna, Pedro Everton Marques Goes, Alexander Tadeu Sverzut, Cassiano Francisco Weege Nonaka, Pollianna Muniz Alves

DOI: 10.1590/S1679-45082018RC4025

ABSTRACT Melanotic neuroectodermal tumor of infancy is a rare and fast-growing neoplasm. In this study, we describe the case of a 6-month-old female patient, who presented swelling in the anterior maxilla. Tomographic reconstruction showed an unilocular hypodense and expansive area associated with the upper right central primary incisor. The presumptive diagnoses were dentigerous cyst, adenomatoid odontogenic tumor, melanotic neuroectodermal tumor of infancy and rhabdomyosarcoma, and an incisional biopsy was performed. Microscopically, the lesion revealed a biphasic cell population, consisting of […]

Influence of growth hormone replacement on neurological and psychomotor development. Case report

Felipe Motta, Adriana Pasmanik Eisencraft, Lindiane Gomes Crisostomo

DOI: 10.1590/S1679-45082018RC3961

ABSTRACT The height response to the use of growth hormone in short height cases has already been confirmed in the literature. The influence of the insulin-like growth factor 1 (GH-IGF1) axis components on development, function, regeneration, neuroprotection, cognition, and motor functions has been evaluated in experimental studies and in adults with central nervous system lesions. However, there is still little research on the clinical impact of hormone replacement on neurological and psychomotor development. This report presents the case of a […]

Correlation between physical examination and three-dimensional gait analysis in the assessment of rotational abnormalities in children with cerebral palsy

Fernando Borge Teixeira, Amando Ramalho, Mauro César de Morais, Danielli Souza Speciali, Catia Miyuki Kawamura, José Augusto Fernandes Lopes, [...]

DOI: 10.1590/S1679-45082018AO4247

Abstract Objective To evaluate the correlation between physical examination data concerning hip rotation and tibial torsion with transverse plane kinematics in children with cerebral palsy; and to determine which time points and events of the gait cycle present higher correlation with physical examination findings. Methods A total of 195 children with cerebral palsy seen at two gait laboratories from 2008 and 2016 were included in this study. Physical examination measurements included internal hip rotation, external hip rotation, mid-point hip rotation […]

Association between hypovitaminosis D and frequency of pulmonary exacerbations in children and adolescents with cystic fibrosis

Renata Ongaratto, Katiana Murieli da Rosa, Juliana Cristina Eloi, Matias Epifanio, Paulo Marostica, Leonardo Araújo Pinto

DOI: 10.1590/S1679-45082018AO4143

Abstract Objective We evaluated the association between vitamin D levels and nutritional status, pulmonary function and pulmonary exacerbations in children and adolescents with cystic fibrosis. Methods 25-hydroxyvitamin D (25(OH)D) levels of 37 children and adolescents were retrospectively evaluated. Pulmonary function, body mass index, height for age, and pulmonary exacerbations episodes were associated with vitamin D levels divided into two groups: sufficient (≥30ng/mL) and hypovitaminosis (

Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats

André Santana, Jean Carlos Debastiani, Pâmela Buratti, Ana Luiza Peretti, Regina Inês Kunz, Rose Meire Costa Brancalhão, [...]

DOI: 10.1590/S1679-45082018AO4137

Abstract Objective To analyze the combined effects of the silk protein sericin and swimming exercise on histomorphometry of the plantar muscle in Wistar rats. Methods Forty adult rats were randomly allocated into 5 groups comprising 8 animals each, as follows: Control, Injury, Sericin, Swim, and Swim plus Sericin. Three days after crushing of the sciatic nerve the rats in the Swim and Swim plus Sericin Groups were submitted to swimming exercise for 21 days. Rats were then euthanized and the […]

European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30: factorial models to Brazilian cancer patients

Juliana Alvares Duarte Bonini Campos, Maria Cláudia Bernardes Spexoto, Wanderson Roberto da Silva, Sergio Vicente Serrano, João Marôco

DOI: 10.1590/S1679-45082018AO4132

ABSTRACT Objective To evaluate the psychometric properties of the seven theoretical models proposed in the literature for European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30), when applied to a sample of Brazilian cancer patients. Methods Content and construct validity (factorial, convergent, discriminant) were estimated. Confirmatory factor analysis was performed. Convergent validity was analyzed using the average variance extracted. Discriminant validity was analyzed using correlational analysis. Internal consistency and composite reliability were used […]

Congenital occipital myelocele

José Ricardo Dias Bertagnon, Marcos Augusto Cruz Rocha, Marina Affonso dos Santos Fonseca Ribeiro, Manuella Pedroza Limongi

DOI: 10.1590/S1679-45082018AI4123

INTRODUCTION Congenital encephalocele is a neural tube closure defect that presents herniation of cranial contents because of a cranial congenital malformation, the occipital encephalocele is the most common form of this defect.() Encephalocele often occur because of occurrence of occipital bone defect within the fourth week of embryogenesis and it can be extended for foramen magnum and affect the posterior arch of the atlas.() Hernia sac content varies and worst prognosis is large brain content inside the sac.(,) Etiology of […]

Patient safety and the value of pharmaceutical intervention in a cancer hospital

Karina da Silva Aguiar, Jamile Machado dos Santos, Mônica Cristina Cambrussi, Solane Picolotto, Marcela Bechara Carneiro

DOI: 10.1590/S1679-45082018AO4122

ABSTRACT Objective To demonstrate economic impact of pharmaceutical evaluation in detection and prevention of errors in antineoplastic prescriptions. Methods This was an observational and retrospective study performed in a cancer hospital. From July to August 2016 pharmacists checked prescriptions of antineoplastic and adjuvant drugs. Drug-related problems observed were classified and analyzed concerning drug, pharmaceutical intervention, acceptability and characteristic of the error. In case of problem related to dose, we calculated a deviation percentage related with correct dose and value spent […]